The club was first opened as Burnham Golf Club on a 9-hole layout designed by Charles Gibson, however the club was extended to an 18-hole layout by Herbert Fowler by 1910 and was renamed to its current name of Burnham & Berrow Golf Club. Even in its early years the course began to host high-level amateur tournaments including the British Ladies Amateur Golf Championship in 1906. 

In 1913 a further redesign of the course was made by Harry Colt which redesigned the course into much of the layout that currently still stands, the work on this redesign was completed in 1923. 

Following the redesigns, the club would go on to host the British Ladies Amateur Golf Championship again in 1923 and 1938 and the 1930 English Amateur. 

The first professional at the club was John Henry Taylor, who would later go on to win five Open Championships and captain Great Britain at the 1933 Ryder Cup. 

The 9-hole Channel course was designed by Fred Hawtree and built in 1977, bringing the total number of holes available to members up to the present-day number of 27. 

In more recent years the championship course has continued to host several top amateur competitions. It has hosted the Brabazon Trophy a further five times in 1990 and 2006 and the English Amateur a further two times in 1981 and 2006. The championship course has also hosted to 1999 Jacques Léglise Trophy and the 2011 Boys Amateur Championship (alongside Enmore Park Golf Club) at Junior level.